by
Dr Hans Christoph Wagner - AVEVE Biochem
The anti-nutritive activities of soluble and insoluble Non-Starch-Polysaccharides (NSP-fibre) are eliminated effectively by supplementation of NSP-multi-enzymes into pig and poultry feed
Firstly, such biological active substances cause a partial degradation of NSP-fibre to smaller molecules hence to reduce highly viscous ingesta.
Secondly, impenetrable cellulosic barriers caused by insoluble NSP-fibre are greatly removed.
Furthermore enzyme linked feed energy upgrading systems enable nutritionists to
precisely recalculate feed formulations on nutrient values and reduced formulation
costs.
The following article will lead through the specific NSPs subject transmitting practical feed formulation tools to reduce feed costs.
Analysing substrate fingerprints to fulfill enzyme lock-key model principles
Feed ingredients consist of non-starch-polysaccharides (NSP) and specified NSP-fibre substrates if observed in context of enzyme physiology. NSP-fibre substrates refer to the largest heterogenic variety of polysaccharide molecules in nature and as mono-gastric animals do not synthesise and release any corresponding digestive enzyme, NSP-fibre substrates are practically indigestible.
In contradiction the chemically α-linked polysaccharide molecules of starch substrates are highly digestible and can be depolymerised by body’s own synthesised amylases enzymes. NSP-enzymes exhibit a high specificity for the corresponding NSP-fibre substrate, hence each enzyme only breaks down a highly specific NSP-fibre substrate.
As NSP-fibre substrates of different feed ingredients consist of various NSP-fibre types their typical NSP- molecule fingerprint, so called – the lock - has to be determined to develop the appropriated NSP-enzyme composition – the key.
The lock-key-principle is the commonly used term to prescribe this unique one-to-one relation. As the efficiency of multi-enzymes is linked to fine-tuned compositions and ratios of different NSP-enzymes, research on complexity of molecule determination of NSP-fibre substrates and a better understanding of NSP-enzymes implied in NSP-fibre degradation is an ongoing and one of the most targeted research focuses in feed additive business.
Categorising negative NSP-fibre effects in layer feed ingredients
The negative effects of NSP-fibre play a crucial role in the digestion process of pig and poultry, might lead to digestive limitations in the gut system and thus have to be considered in developing feed formulations. These negative effects can be categorised into two groups.
Firstly, NSP-fibre can increase the viscosity in the intestine by their high water binding capacity. As a consequence increased viscosity slows down the migration and absorption of nutrients, lowers the feed intake and reduces the access of digestive enzymes synthesised and released by the animal itself.
The commonly used synonym to prescribe this phenomenon is the “Gel effect”. Secondly, insoluble NSP-fibre can encapsulate feed nutrients which become less accessible for digestion and absorption in the relatively small intestine.
These nutrients enter undigested the large intestine where they become a substrate for unintended bacterial fermentation. The commonly used synonym to prescribe this phenomenon is the “Nut shell effect”.
Digesting NSP-fibre of feed ingredients by cutting the glycosidical bonds of polysaccharide molecules and taking advantage of nutrients encapsulated by NSP-fibre, the use of a substrate adapted NSP-multi-enzyme in feed is the only available but also most effective choice.
Read the full article, HERE.
Visit the AVEVE Biochem website, HERE.
The anti-nutritive activities of soluble and insoluble Non-Starch-Polysaccharides (NSP-fibre) are eliminated effectively by supplementation of NSP-multi-enzymes into pig and poultry feed
Firstly, such biological active substances cause a partial degradation of NSP-fibre to smaller molecules hence to reduce highly viscous ingesta.
Secondly, impenetrable cellulosic barriers caused by insoluble NSP-fibre are greatly removed.
 |
| Image credit: Steven Lilley on Flickr (CC BY-SA 2.0) |
The following article will lead through the specific NSPs subject transmitting practical feed formulation tools to reduce feed costs.
Analysing substrate fingerprints to fulfill enzyme lock-key model principles
Feed ingredients consist of non-starch-polysaccharides (NSP) and specified NSP-fibre substrates if observed in context of enzyme physiology. NSP-fibre substrates refer to the largest heterogenic variety of polysaccharide molecules in nature and as mono-gastric animals do not synthesise and release any corresponding digestive enzyme, NSP-fibre substrates are practically indigestible.
In contradiction the chemically α-linked polysaccharide molecules of starch substrates are highly digestible and can be depolymerised by body’s own synthesised amylases enzymes. NSP-enzymes exhibit a high specificity for the corresponding NSP-fibre substrate, hence each enzyme only breaks down a highly specific NSP-fibre substrate.
As NSP-fibre substrates of different feed ingredients consist of various NSP-fibre types their typical NSP- molecule fingerprint, so called – the lock - has to be determined to develop the appropriated NSP-enzyme composition – the key.
The lock-key-principle is the commonly used term to prescribe this unique one-to-one relation. As the efficiency of multi-enzymes is linked to fine-tuned compositions and ratios of different NSP-enzymes, research on complexity of molecule determination of NSP-fibre substrates and a better understanding of NSP-enzymes implied in NSP-fibre degradation is an ongoing and one of the most targeted research focuses in feed additive business.
Categorising negative NSP-fibre effects in layer feed ingredients
The negative effects of NSP-fibre play a crucial role in the digestion process of pig and poultry, might lead to digestive limitations in the gut system and thus have to be considered in developing feed formulations. These negative effects can be categorised into two groups.
Firstly, NSP-fibre can increase the viscosity in the intestine by their high water binding capacity. As a consequence increased viscosity slows down the migration and absorption of nutrients, lowers the feed intake and reduces the access of digestive enzymes synthesised and released by the animal itself.
The commonly used synonym to prescribe this phenomenon is the “Gel effect”. Secondly, insoluble NSP-fibre can encapsulate feed nutrients which become less accessible for digestion and absorption in the relatively small intestine.
These nutrients enter undigested the large intestine where they become a substrate for unintended bacterial fermentation. The commonly used synonym to prescribe this phenomenon is the “Nut shell effect”.
Digesting NSP-fibre of feed ingredients by cutting the glycosidical bonds of polysaccharide molecules and taking advantage of nutrients encapsulated by NSP-fibre, the use of a substrate adapted NSP-multi-enzyme in feed is the only available but also most effective choice.
Read the full article, HERE.
Visit the AVEVE Biochem website, HERE.
The Global Miller
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