15/06/2016: The one and only feedase – a new enzyme solution launched by Adisseo

A 10-year research program in bio-engineering and animal nutrition, is about to revolutionise feed digestibility.

A new feedase enzyme solution from Adisseo, called Rovabio® Advance, can improve the digestibility of all feed nutrients, including amino acids, phosphorus and calcium, whatever the type of diet.

Arabinofuranosidases - the key debranching enzymes
Rovabio® Advance’s efficacy is explained by the unique presence of arabinofuranosidases (ABFs); a very important kind of debranching enzyme. 

    
These enzymes work synergistically with xylanases to efficiently break down complex fibre structures in plant cell walls.

By removing hampering branches from fibres, these enzymes open room to allow the xylanases access to the backbone of the fibre chain, greatly boosting their efficacy.
     

Performance trials proving the potential of Rovabio® Advance to save three percent AME and dAA

In addition, there are two newly expressed kinds of xylanases (XynC, XynG) in Rovabio® Advance, as well as an increased presence of XynB and XynD compared to the former product, Rovabio® Excel.

This large range of xylanases, in combination with ABFs, explains the consistency of the results regardless of the feed composition.

An innovative approach
“The classical method to produce an enzyme is the random integration of the gene of interest in the strain. However, this method allows production of only a single enzyme,” explains Olivier Guais, PhD, Biochemistry Development Manager at Adisseo.

”We had to think outside of the box for the development of the most efficient combination of enzymes.”

Specific work on the regulation of the transcription of genes coding for enzymes of interest expression by the fungus Talaromyces versatilis was carried out. This led to an overproduction of the targeted key enzymes while keeping versatility thanks to the broad range of enzymes produced by this microorganism, such as beta-glucanases, cellulases, pectinases, mannanases, and several others.
       
Proven efficacy
Robust testing across a variety of diets shows that Rovabio® Advance provides improvement in the order of three percent in the overall digestibility of organic matter, supported by a higher digestive retention of starch, protein, and fat. 

       
Thanks to the degradation of the cell wall of vegetable raw material, nutrients’ accessibility to endogenous enzymes is improved.

Whatever the type of diet (wheat- or corn-based diets) or energy level of the diet, a consistent improvement of three percent AME, three percent dAA and P and Ca availability has been proven.
    

Performance trials proving the potential of Rovabio® Advance to save three percent AME and dAA

Many trials evaluating the performance and carcass parameters of broilers based on reformulated diets for a reduction in nutrient level confirm that, with the addition of Rovabio® Advance, AME and dAA content in feed can be reduced by three percent, ensuring the same performance (FCR and BWG) compared with a positive control diet (see graphics).

Thus, Rovabio® Advance is the only feedase, the perfect combination of enzymes, to improve the availability of all nutrients of the feed, whatever the type of diet.

Unique benefits
The product is now authorised in most parts of the world and is available in different forms (powder at 50g/MT of feed or liquid at 100 to 200mL/MT) to fit various feedmill applications.

“This is a major innovation for the feed industry, leading to an unmatched reduction of costs and reduction of nutrient losses,” says Frank Chmitelin, Vice-President of Global Sales and Marketing Director.

With a potential to replace three percent of the AME and digestible amino acids, Adisseo offers the possibility to decrease the feed cost by €12/MT of feed treated with Rovabio® Advance.

In a feedmill producing 100,000 MT of broiler or turkey feed per year, Rovabio® Advance generates an extra margin of at least €300,000 per year compared to former generations of NSP enzymes. 

Visit the Adisseo site HERE. 

The Global Miller
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